WASHINGTON — The annual anti-abortion rally in the nation’s capital sounded more like a victory celebration Friday as speaker after speaker expressed a growing sense of optimism that their long-sought goal was finally in reach: a sweeping rollback of abortion rights in America.

Thousands of anti-abortion protesters rallied in the bitter cold and then marched to the Supreme Court, which has indicated it will allow states to impose tighter restrictions on abortion with a ruling in the coming months — and possibly overturn the landmark 1973 Roe v. Wade ruling that affirmed the constitutional right to an abortion.

“It doesn’t feel real. There’s so much hope and vibrancy and happiness and joy at this thing,” said Jordan Moorman of Cincinnati. “I really do believe that we’re in a post-Roe generation.”

The annual March for Life rally, held one day before the 49th anniversary of the Roe decision, took place amid a COVID-19 surge that limited turnout at the National Mall. Some abortion opponents posted on the event’s Facebook page that they would not attend because of COVID-19 vaccine mandates for people going to restaurants and other places in the District of Columbia.

Still, the rally drew a crowd of thousands, with a heavy contingent of young people and students bussed in by schools and church groups. The mood was overwhelmingly upbeat, with many treating the end of Roe v. Wade as inevitable.

Jeanne Mancini, president of the March for Life Education and Defense Fund, told the crowd that Roe is not settled law and “we are hoping and praying that this year, 2022, will bring a historic change for life.”

“If Roe falls, the battle lines will change, but make no mistake the fight for life will need to continue in the states and here in D.C.,” Mancini said.

The Rev. Andrew Rudmann, a Catholic priest from New Orleans, was attending his 11th event. “Hopefully this will be the last March for Life,” he said.

Rudmann said previous marches may have had larger crowds but he doesn’t recall this level of optimism. He said the crowds grew “gigantic” under former President Donald Trump and the movement’s enthusiasm grew with each Trump Supreme Court appointee. He proudly pointed out that his home Archdiocese of New Orleans includes the Catholic high school that educated Trump’s last appointee, Supreme Court Justice Amy Coney Barrett.

“Sometimes I would come to the March and it would be great to be united with people who share my beliefs, but there would also be this heaviness,” he said. “This time the whole language and vibe is different.”

After the rally, the crowd marched to the Supreme Court with chants that included: “We love babies, yes we do, we love babies, how bout you?” and “Hey hey, ho ho, Roe v. Wade has got to go!”

The celebratory and triumphant mood of the day was perhaps best encapsulated by a contingent from New York City that bounced past the Supreme Court building with dancing nuns and drummers playing Latin rhythms.

Abortion rights groups worry that at least 26 states are in line to further limit abortion access if Roe is weakened or overturned. In December, the court indicated in a major case that it would uphold a Mississippi ban on abortions after 15 weeks of pregnancy, and allow states to ban abortion even earlier. The Mississippi case directly challenges Roe.

Courts have also dealt Texas abortion providers a string of defeats over efforts to block a law that since September has banned abortions once cardiac activity is detected, which is usually around six weeks and before some women know they are pregnant. Another loss for Texas clinics came Thursday, when the Supreme Court refused to speed up the ongoing challenge over the law, which providers say is now likely to stay in effect for the foreseeable future.

“This law is cruel and unconstitutional, and I am deeply disappointed that our judicial system has done very little to stop it,” said Amy Hagstrom Miller, president of Whole Woman’s Health, which operates four abortion clinics in Texas.

Lawmakers from both parties weighed in Friday to note the anniversary of Roe v. Wade and reflect on the shifting political landscape surrounding abortion.

“It has been an eye-opening year for the cause of life in America, and we have made significant progress in defending our youngest and most vulnerable,” said Rep. Kevin McCarthy, the Republican leader in the House.

“The stakes are higher than ever, with the health and autonomy of women and families across the country hanging in the balance as Republicans work to methodically challenge and overturn Roe,” said Sen. Jeanne Shaheen, D-N.H. “It’s time to sound the alarm and make clear: decisions about our bodies, our health care and our future belong to us.”

Dozens of GOP lawmakers appeared at the march personally or as part of a video voicing their allegiance with those in attendance. White House press secretary Jen Psaki took note of the anniversary of the Roe v. Wade ruling as part of Friday’s press briefing, saying that “reproductive health care has been under extreme and relentless assault ever since, especially in recent months.”

She said the Biden administration was committed to working with Congress to pass a bill that protects the right to provide and access abortion care free from forced waiting periods, biased counseling and other restrictions.

“We’re deeply committed to making sure everyone has access to care and we will defend it with every tool we have,” Psaki said.

Mississippi state Sen. Joey Fillingane, a Republican who pushed for the state’s strict abortion laws, said that if Roe were nullified, he expects states to take different approaches to setting their own abortion laws.

“I think that’s the way it should be,” he said. “The laws in California, based on their population and what they want, may be very different than the laws in Mississippi based on what our population feels about the issue of life.