New York’s Isiah Kiner-Falefa, left, runs to first after hitting a single to drive in Greg Allen, right, in the 10th inning of the Yankees’ 3-2 win over San Diego on Saturday in New York. Bebeto Matthews/Associated Press

NEW YORK — Isiah Kiner-Falefa hit a game-ending single with one out in the 10th inning as the New York Yankees beat the San Diego Padres 3-2 on Saturday.

After Anthony Volpe and Aaron Judge hit into double plays in the eighth and ninth, the Yankees got their fifth walk-off win when Kiner-Falefa sent Nick Martinez’s 2-0 pitch down the line just past the glove of third baseman Rougned Odor to score Greg Allen.

DJ LeMahieu, who had an RBI double in the first, homered off Padres starter Michael Wacha to tie it in the seventh as the Yankees avoided a fourth straight loss.

Fernando Tatis Jr. homered for the second straight game, and ninth time this season, for San Diego’s only hit in Luis Severino’s 6 2/3 innings. Ha-Seong Kim hit an RBI single in the seventh off Michael King.

Severino allowed two runs, one earned, in his second start since returning from a strained right lat.

Clay Holmes (3-2), who came on in the top of the 10th, retired Tatis on a soft grounder that was initially ruled an infield hit before being overturned on replay to end the inning.

Wacha allowed two runs and five hits before turning the game over to Martinez (2-2) for the final 2 1/3 innings.

DODGERS 6, RAYS 5: Freddie Freeman extended his hitting streak to 16 games, Max Muncy and Miguel Vargas homered, and NL West-leading Los Angeles beat the MLB-best Tampa Bay in St. Petersburg, Florida.

Freeman finished 2 for 3 with two walks and is hitting .444 (28 for 63) with 18 RBI during his streak.

Mookie Betts had an RBI single and Freeman followed with a run-scoring double off Colin Poche (3-1) as Los Angeles took a 5-4 lead in the seventh inning. Vargas added a solo shot in the eighth.

NATIONALS 4, ROYALS 2: CJ Abrams hit a two-run double in Washington’s four-run sixth inning, Corey Dickerson got his 1,000th career hit and Washington won in Kansas City, Missouri.

Dickerson sparked the Nationals’ big inning with his milestone hit on an RBI double. He became the 12th player to reach the milestone in a Nationals uniform and the first since Brian Dozier in 2019.

MARINERS 5, PIRATES 0: Luis Castillo struck out 10 in six crisp innings, and Seattle won at home.

Castillo allowed one hit — Tucupita Marcano’s double on the game’s first pitch — and walked two. The right-hander earned his second straight win since dropping consecutive starts.

Gabe Speier, Matt Brash, Trevor Gott and Justin Topa then combined for three innings of one-hit ball for Seattle.

AMERICAN LEAGUE

TIGERS 7, WHITE SOX 3: Zach McKinstry homered in a three-run seventh as host Detroit rallied to beat Chicago.

McKinstry went 3 for 4 with a sacrifice fly and has reached base 19 times in the last seven games.

The Tigers trailed 3-2 going into the bottom of the seventh, but McKinstry tied the game with a one-out homer off Joe Kelly (1-3), and back-to-back doubles by Riley Greene and Spencer Torkelson gave Detroit a 4-3 lead.

Torkelson took third on a wild pitch and Eric Haase punched a single over the drawn-in infield to make it 5-3.

TWINS 9, BLUE JAYS 7: Willi Castro had his first career multi-homer game, Matt Wallner homered amongst his career-high four hits, and Minnesota held off Toronto in Minneapolis.

Edouard Julien also homered as part of a three-hit day, and Alex Kirilloff and Kyle Farmer each had two of Minnesota’s 14 hits.

Bo Bichette had three hits, including a home run the second straight game, but the Blue Jays lost for the 10th time in 13 games. Daulton Varsho also went deep.

ASTROS 6, ATHLETICS 2: Astros’ shortstop Jeremy Peña hit a two-run home run in his first at-bat since getting a planned day off, backing another solid outing from Framber Valdez as Houston won in Oakland, California to send the Athletics to their 10th consecutive loss.

Alex Bregman had three hits and three RBI for Houston, which has won 13 of 16.

The victory was the 2,123rd of Astros manager Dusty Baker’s career, two shy of Hall of Famer Joe McCarthy for eighth on the all-time list.

RANGERS 5, ORIOLES 3: Andrew Heaney pitched seven innings of four-hit ball, Marcus Semien extended his hitting streak to 16 games with a pivotal two-run single and Texas won in Baltimore.

Robbie Grossman and Jonah Heim had an RBI single apiece for the Rangers, who have won 10 of 13. Their 33-18 record is best in Rangers history after 51 games, and they passed Baltimore (33-19) for second-best in the majors behind Tampa Bay.

After outscoring the Orioles 17-5 in the first two games of this three-game set, Texas is assured of winning a fifth straight road series for the first time since 2016.

NATIONAL LEAGUE

PHILLIES 2, BRAVES 1: Zack Wheeler struck out 12 in eight shutout innings, and Philadelphia beat Charlie Morton and the Braves in Atlanta.

Wheeler (4-4) allowed three hits, walked one and hit a batter in his first win since April 29. The right-hander went 0-3 with a 4.44 ERA in four previous May starts.

Philadelphia went ahead to stay with two runs in the fifth against Morton (5-5). Bryson Stott drove in Brandon Marsh with a sacrifice fly, and Trea Turner added a run-scoring double.

GIANTS 3, BREWERS 1: Mitch Haniger hit a go-ahead two-run homer in the eighth inning and Logan Webb allowed one run over seven innings to pace San Francisco to a win in Milwaukee.

J.D. Davis singled with one out in the eighth off Peter Strzelecki, who relieved to open the inning. After Michael Conforto struck out, Haniger sent the first pitch he saw from Strzelecki (2-4) 419 feet to center for his fourth homer.

That big hit came a night after Haniger, originally drafted by the Brewers, went 3 for 5 with a homer and four RBIs in the Giants’ 15-1 victory over Milwaukee.

NOTES

BREWERS: Shortstop Willy Adames was placed on the seven-day concussion list after getting hit in the head by a foul ball in the dugout the previous night during Milwaukee’s game against the San Francisco Giants.

Adames was taken to the hospital after being hit a liner off the bat of teammate Brian Anderson in the bottom of the second inning. Brewers Manager Craig Counsell said Adames was released from the hospital on Saturday morning.